Shortage of Medicines
Speculators: When enemy camps were overrun, speculators raided the medical stores capturing morphine, quinine and chloroform to resell at 50 times their original value. It was such a problem that General Lee called upon the secretary of war to put an end to the practice.
A well known manual on indigenous substitutes written by surgeon Maj. Francis Perye Porcher was “Resources of the Southern Fields and Forests, Medical, Economic and Agricultural.”
Published in 1863, the 600-page book was distributed to medical officers to help aid the sick and wounded. It is said to have helped so many that Confederates were able to hold off the Union Army for two additional years.

Eupatorium, known as boneset, was a substitute for quinine. It is also
known to be used by slaves of the southern plantations to treat typhus.
Other medicinal substitutes used by Confederate surgeons included blackberry roots, charcoal, wild lettuce, peach leaf tea, rhubarb and a cordial made from persimmon and sugar to treat diarrhea and dysentery. These substitutes were undoubtedly less toxic than Union medical personnel’s affinity for mercury, used to treat everything from dysentery to headaches.
article source: TimeRecord News, Wichita Falls, Texas